Strong demographics make Lisle a desirable location for businesses. The 2010 census had determined Lisle's population to be 22,390, and Nielsen's 2013 research estimates that there are approximately 256,475 people within a 5-mile radius of Downtown Lisle.
This includes 100,878 households with an estimated average household income of $103,973. The estimated median value of owner-occupied housing is $274,794.
During the day, Lisle's population increases to approximately 36,960 as employees commute to business districts and visitors travel to many community treasures, such as the Morton Arboretum, which welcomed more than 1.2 million visitors in 2019.
In particular, the I-88 Corporate Corridor is a strong generator of visitors due, in part, to the business headquarters located along the corridor (such as Navistar and SunCoke Energy), four hotels (DoubleTree, Hyatt, Sheraton, Extended Stay), the DuPage Medical Group Cancer Treatment Center, Choose DuPage and workNet DuPage, UTI (United Technical Institute) and more.